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Chai Hu Gui Zhi Tang is a classic Traditional Chinese Medicine (TCM) formula first recorded in the *Shanghan Lun* (Treatise on Febrile Diseases) by Zhang Zhongjing. It is a combination of two foundational formulas: Xiao Chai Hu Tang (Minor Bupleurum Decoction) and Gui Zhi Tang (Cinnamon Twig Decoction). The decoction typically consists of nine herbal ingredients: *Radix Bupleuri* (Chai Hu), *Ramulus Cinnamomi* (Gui Zhi), *Radix Paeoniae Alba* (Bai Shao), *Rhizoma Pinelliae* (Ban Xia), *Radix Scutellariae* (Huang Qin), *Radix et Rhizoma Ginseng* (Ren Shen), *Radix et Rhizoma Glycyrrhizae* (Gan Cao), *Rhizoma Zingiberis Recens* (Sheng Jiang), and *Fructus Jujubae* (Da Zao). Traditionally used to treat concurrent Taiyang and Shaoyang syndromes, it is characterized by symptoms such as fever, chills, joint pain, and nausea. In modern clinical research, it is investigated for its anti-inflammatory, analgesic, and cardioprotective properties, with specific interest in its efficacy for stable angina pectoris, epilepsy, and chronic gastritis.
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