Drug intelligence / Profile preview

Chai Mu jiaqiang Decoction

Development stage
Preclinical
Lead developer
Nanjing University of Chinese Medicine
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Chai Mu jiaqiang Decoction is a traditional Chinese medicine (TCM) herbal decoction being developed by Nanjing University of Chinese Medicine for the treatment of depression. It is a strengthened formulation of the traditional Chai Mu (Bupleurum and Oyster Shell) formula, designed to improve the onset of antidepressant effects and alleviate insomnia. The decoction is being evaluated in clinical trials in China, including a multicenter, randomized, open-label, parallel-group controlled trial comparing its efficacy and safety, both alone and in combination with other regimens, against escitalopram-based control regimens.

Other names
Chai Mu jiaqiang formulaChai Mu jiaqiang Tangstrengthened Chai Mu formula

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