Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
chaihu longgu muli decoction
- Development stage
- Unknown
- Lead developer
- The Second People's Hospital of Hunan Province
- Administration
- Oral
01
Overview
Chaihu Longgu Muli Decoction (CLMD) is a classic Traditional Chinese Medicine (TCM) formula first documented in the 'Shanghan Lun' (Treatise on Febrile Diseases). It is a complex multi-herb decoction traditionally used to treat neuropsychiatric conditions characterized by 'liver qi stagnation' and 'disturbed spirit,' including epilepsy, anxiety, depression, and insomnia. The formula typically consists of Radix Bupleuri (Chaihu), Fossilia Ossis Mastodi (Longgu), Concha Ostreae (Muli), Radix Scutellariae (Huangqin), Rhizoma Pinelliae (Banxia), Zingiber officinale (Shengjiang), Radix et Rhizoma Rhei (Dahuang), Cinnamomum cassia (Guizhi), Poria cocos (Fuling), Panax ginseng (Renshen), and Ziziphus jujuba (Dazao). Modern clinical research, such as studies conducted at Hu'nan Brain Hospital, explores its neuroprotective mechanisms in temporal lobe epilepsy, specifically focusing on its ability to modulate autophagy through exosome-mediated miRNA pathways.
- Other names
- Chaihu-Longgu-Muli-TangChaihu Longgu Muli WanChai Hu Long Gu Mu Li Tang
02
Targets
IL1B (Interleukin-1 beta)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL-6 (Interleukin 6)MAPK3 (Mitogen-activated protein kinase 1)
Beyond the preview
Go deeper on chaihu longgu muli decoction.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on chaihu longgu muli decoction.