Drug intelligence / Profile preview

Chaihu nasal spray

Development stage
Preclinical
Lead developer
Fudan University
Modality
Small Molecules
Administration
Intranasal
01

Overview

Chaihu nasal spray is a Traditional Chinese Medicine (TCM)-derived pharmaceutical candidate developed by researchers at Fudan University for the treatment of the common cold and fever. The formulation utilizes the volatile oils or active components, such as saikosaponins, extracted from Radix Bupleuri (Chaihu). It is designed for intranasal administration to provide rapid antipyretic and anti-inflammatory effects by facilitating absorption through the nasal mucosa, potentially bypassing first-pass metabolism and offering a faster onset of action compared to traditional oral TCM formulations. The drug aims to reduce body temperature and alleviate symptoms associated with upper respiratory tract infections through the modulation of inflammatory mediators.

Other names
Bupleurum nasal sprayChaihu Antipyretic Nasal Spray柴胡鼻喷雾剂
02

Targets

IL-6 (Interleukin 6)

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