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chailian ganmao granules
- Development stage
- Phase 2
- Lead developer
- Huixian Baiquan Traditional Chinese Medicine Research and Development
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Chailian Ganmao Granules is a Traditional Chinese Medicine (TCM) formulation primarily used for the treatment of wind-heat type common cold and acute upper respiratory tract infections. Developed and manufactured by companies such as Wuhan Shuanglong Pharmaceutical, the granules are a combination of several herbal extracts, including *Bupleurum chinense* (Chaihu), *Scutellaria baicalensis* (Huangqin), and *Forsythia suspensa* (Lianqiao). Its mechanism of action involves antipyretic, anti-inflammatory, and antiviral properties, aimed at clearing heat and detoxifying the body (Jie Biao Qing Re, Xie Huo Jie Du). Pharmacologically, it works by inhibiting inflammatory mediators such as prostaglandin E2 (via COX-2 inhibition) and reducing the levels of pro-inflammatory cytokines like TNF-alpha and IL-6. It is indicated for symptoms including fever, headache, sore throat, and cough associated with wind-heat syndrome.
- Brand names
- Chailian Ganmao Granules
- Other names
- Chailian Ganmao Keli柴连感冒颗粒
02
Targets
IL-6 (Interleukin 6)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))
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