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Chaiyin granules
- Development stage
- Unknown
- Lead developer
- China-Japan Friendship Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Chaiyin granules is a Traditional Chinese Medicine (TCM) formulation developed for the treatment of influenza and other upper respiratory tract infections. It is specifically indicated for patients presenting with exogenous wind-heat syndrome, characterized by symptoms such as fever, sore throat, and cough. The formulation is derived from a combination of herbal extracts, most notably *Bupleurum chinense* (Chaihu) and *Lonicera japonica* (Jinyinhua), which are recognized in TCM for their antipyretic, anti-inflammatory, and antiviral properties. Clinical research, including multicenter trials sponsored by the China-Japan Friendship Hospital, has focused on evaluating its efficacy in reducing fever duration and symptom severity compared to standard antiviral treatments.
- Brand names
- Chaiyin Keli
- Other names
- Chaiyin KeliChai Yin Ke Li
02
Targets
IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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