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Chamomilla Supreme is a dietary supplement developed by Supreme Nutrition Products, consisting of high-quality powdered German Chamomile (*Matricaria recutita*). It is utilized for its broad-spectrum therapeutic properties, including its role as a carminative for digestive distress, a mild sedative for anxiety and sleep support, and an anti-inflammatory agent. The pharmacological profile of the supplement is driven by its rich content of flavonoids and terpenoids. Specifically, the flavonoid apigenin acts as a ligand for central GABA-A receptors, providing mild sedative and anxiolytic effects. Additionally, essential oil components such as alpha-bisabolol and chamazulene exert anti-inflammatory and antispasmodic actions by inhibiting the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, thereby reducing inflammatory mediators and smooth muscle contraction in the gastrointestinal tract.
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