Drug intelligence / Profile preview

Chamomilla Supreme

Development stage
Unknown
Lead developer
Supreme Nutrition Products
Modality
Small Molecules
Administration
Oral
01

Overview

Chamomilla Supreme is a dietary supplement developed by Supreme Nutrition Products, consisting of high-quality powdered German Chamomile (*Matricaria recutita*). It is utilized for its broad-spectrum therapeutic properties, including its role as a carminative for digestive distress, a mild sedative for anxiety and sleep support, and an anti-inflammatory agent. The pharmacological profile of the supplement is driven by its rich content of flavonoids and terpenoids. Specifically, the flavonoid apigenin acts as a ligand for central GABA-A receptors, providing mild sedative and anxiolytic effects. Additionally, essential oil components such as alpha-bisabolol and chamazulene exert anti-inflammatory and antispasmodic actions by inhibiting the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, thereby reducing inflammatory mediators and smooth muscle contraction in the gastrointestinal tract.

Brand names
Chamomilla Supreme
Other names
German ChamomileMatricaria recutita
02

Targets

GABRA2 (Gamma-aminobutyric acid receptor subunit alpha 2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)

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