Drug intelligence / Profile preview

CHATreg-101

Development stage
Unknown
Lead developer
CHA Biotech
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Tumor-Infiltrating Lymphocytes (TILs) → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
01

Overview

CHATreg-101 is an **autologous regulatory T cell cell therapy** being developed by **CHA Biotech** as an immunomodulatory treatment for **graft-versus-host disease** and autoimmune diseases including **rheumatoid arthritis**, **systemic lupus erythematosus**, and **inflammatory bowel disease**. The product uses a patient's own **regulatory T cells** to suppress pathogenic immune responses and restore immune tolerance, which is the core therapeutic rationale for Treg-based cell therapy in alloimmune and autoimmune disorders. Based on CHA Biotech's pipeline materials, CHATreg-101 is being advanced under Korea's Advanced Regenerative Bio Act framework in a **clinical research and early access** setting, consistent with early-stage clinical development.

Other names
autologous Treg cell therapy

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