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Chi-Huang is a traditional Chinese medicine (TCM) topical formulation investigated primarily for its anti-inflammatory and anti-pruritic effects, especially in dermatological contexts such as allergic contact dermatitis and canine atopic dermatitis. Experimental data in murine models indicate that Chi-Huang cream reduces skin lesions, scratching, and skin thickness, with efficacy comparable to hydrocortisone butyrate and fewer adverse effects. Its use as a solution has been researched for allergic pruritus in both animals and humans, and it is considered a promising TCM therapy for chronic pruritus, showing immunomodulatory and anti-inflammatory properties[1][2][3].
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