Drug intelligence / Profile preview

CHIK

Development stage
Unknown
Lead developer
Valneva
Modality
Vaccines & Immunotherapeutics
01

Overview

CHIK is an abbreviation primarily used for Chikungunya virus and Chikungunya fever, a mosquito-borne viral illness. In the context of drug development, 'CHIK' often refers to the Chikungunya virus or its components when used as an active ingredient in investigational vaccines, such as MV-CHIK and ChAdOx1 Chik, which aim to induce an immune response to prevent infection. It also denotes the Chikungunya virus protease (CHIKVP), a key target for antiviral drug development. The 'chik sign' is a distinct clinical marker of nasal hyperpigmentation associated with Chikungunya fever.

Other names
Chikungunya virusChikungunya fever
02

Targets

TLR4 (Toll-like receptor 4)TLR2 (Toll-like Receptor 2)

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