Drug intelligence / Profile preview

chimeric anti-carcinoembryonic antigen monoclonal antibody-fluorescein conjugate

Development stage
Unknown
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Antibody Conjugates → Antibody-Based Therapeutics
Administration
Not Specified
01

Overview

This is a conjugated chimeric (human-mouse) monoclonal antibody targeting carcinoembryonic antigen (CEA), chemically linked to fluorescein for detection purposes, likely for in vitro or ex vivo diagnostic applications such as immunohistochemistry or flow cytometry. The chimeric antibody design reduces immunogenicity compared to purely murine antibodies. While there is extensive literature on chimeric anti-CEA monoclonal antibodies (e.g., cT84.66) labeled with radioisotopes for imaging and therapy in clinical trials[1], there is no specific published information in the provided search results regarding a fluorescein conjugate of this molecule.

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