Drug intelligence / Profile preview

China Pharma Univ. BRD4 BD1 compound 12m

Development stage
Unknown
Lead developer
China Pharmaceutical University
01

Overview

China Pharma Univ. BRD4 BD1 compound 12m: sourced facts only. name: "Among them, the representative compound 12m showed potent BRD4 BD1 inhibitory activity, of which the inhibition rate is better than the other compounds." [PMID:39823809]; target: "Among them, the representative compound 12m showed potent BRD4 BD1 inhibitory activity, of which the inhibition rate is better than the other compounds." [PMID:39823809]; developer: "Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China." [PMID:39823809]; stage: "In MV4-11 cell line, compound 12m also showed excellent anti-cancer activity (IC50 = 0.02 μM), which is superior to (+)-JQ1 (IC50 = 0.03 μM)." [PMID:39823809]

02

Targets

BRD4 (Bromodomain-containing protein 4)

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