Drug intelligence / Profile preview

China Pharma Univ. HDAC1 compound 17q

Development stage
Preclinical
Lead developer
China Pharmaceutical University
01

Overview

China Pharma Univ. HDAC1 compound 17q: sourced facts only. name: "Among them, compound 17q exhibited potent inhibition of HDAC1/2/3/6, with good antiproliferative activity in vitro and an excellent pharmacokinetic profile." [PMID:38503167]; target: "Among them, compound 17q exhibited potent inhibition of HDAC1/2/3/6, with good antiproliferative activity in vitro and an excellent pharmacokinetic profile." [PMID:38503167]; developer: "State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing, 210009, China." [PMID:38503167]; stage: "Compound 17q significantly inhibited tumor growth in a DU145 xenograft tumor model and showed no obvious toxicity." [PMID:38503167]

02

Targets

HDAC1 (Histone Deacetylase 1)

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