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China Pharma Univ. hDHODH compound H19
- Development stage
- Unknown
- Lead developer
- China Pharmaceutical University
01
Overview
China Pharma Univ. hDHODH compound H19: sourced facts only. name: "Overall, H19 emerges as a promising hDHODH inhibitor with potential anticancer properties warranting development." [PMID:38941701]; target: "Overall, H19 emerges as a promising hDHODH inhibitor with potential anticancer properties warranting development." [PMID:38941701]; developer: "Jiangsu Key Laboratory of Bioactive Natural Product Research, State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, People's Republic of China." [PMID:38941701]; stage: "Further pharmacological investigations revealed that H19 exerted anticancer effects by inducing ferroptosis in NCI-H226 cells, with its cytotoxicity being reversed by ferroptosis inhibitors." [PMID:38941701]
02
Targets
DHODH (Dihydroorotate dehydrogenase (quinone), mitochondrial)
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