Drug intelligence / Profile preview

China Pharma Univ. PAK4 compound 27e

Development stage
Unknown
Lead developer
China Pharmaceutical University
01

Overview

China Pharma Univ. PAK4 compound 27e: sourced facts only. name: "Compounds 27e, 27g, 27i and 27j were found to exhibit potent inhibitory activity against PAK4 (IC50 = 10, 13, 11 and 9 nM, respectively)." [PMID:37864885]; target: "Compounds 27e, 27g, 27i and 27j were found to exhibit potent inhibitory activity against PAK4 (IC50 = 10, 13, 11 and 9 nM, respectively)." [PMID:37864885]; developer: "Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China." [PMID:37864885]; stage: "Subsequent cellular assay demonstrated that compound 27e possessed the strongest antiproliferative activity against A549 cells with an IC50 value of 0.61 μM, a little bit better than PF-3758309." [PMID:37864885]

02

Targets

PAK4

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