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China Pharma Univ. PD-L1 compound B9
- Development stage
- Unknown
- Lead developer
- China Pharmaceutical University
01
Overview
China Pharma Univ. PD-L1 compound B9: sourced facts only. name: "Among them, B9 was found to inhibit the PD-1/PD-L1 interaction with the best IC50 value of 1.8 ± 0.7 nM." [PMID:38109261]; target: "Among them, B9 was found to inhibit the PD-1/PD-L1 interaction with the best IC50 value of 1.8 ± 0.7 nM." [PMID:38109261]; developer: "School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China." [PMID:38109261]; stage: "Furthermore, B9 displayed high in vivo antitumor efficacy in the CT26 mouse model and activated the immune microenvironment and induced PD-L1 degradation of PD-L1 in the tumor." [PMID:38109261]
02
Targets
CD274 (Programmed cell death protein 1 ligand 1)
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