China Pharma Univ. PI3Kα compound 27

China Pharma Univ. PI3Kα compound 27: sourced facts only. name: "Compound 27 was determined with potent PI3Kα inhibitory activity (IC50 = 4.4 nM), which exhibited excellent selectivity for homologous PI3K enzymes and a 370 kinome panel." [PMID:35834807]; target: "Compound 27 was determined with potent PI3Kα inhibitory activity (IC50 = 4.4 nM), which exhibited excellent selectivity for homologous PI3K enzymes and a 370 kinome panel." [PMID:35834807]; developer: "State Key Laboratory of Natural Medicines and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China." [PMID:35834807]; stage: "Importantly, compound 27 exerted great antigastric cancer activity in vivo when combined with taxol." [PMID:35834807]