Drug intelligence / Profile preview

China Pharma Univ. SND1 compound C19

Development stage
Preclinical
Lead developer
China Pharmaceutical University
01

Overview

China Pharma Univ. SND1 compound C19: sourced facts only. name: "The representative compound C19 showed potent activity against MTDH-SND1 PPI with an IC50 of 487 ± 99 nM and tight binding to the SND1-purified protein with a Kd value of 279 ± 17 nM." [PMID:39792778]; target: "The representative compound C19 showed potent activity against MTDH-SND1 PPI with an IC50 of 487 ± 99 nM and tight binding to the SND1-purified protein with a Kd value of 279 ± 17 nM." [PMID:39792778]; developer: "State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China." [PMID:39792778]; stage: "In addition, compound C19 exhibited promising tumor growth inhibition in the xenograft model." [PMID:39792778]

02

Targets

NFKB2 (NF-κB2)

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