Drug intelligence / Profile preview

China Pharma Univ. Wee1 compound 12h

Development stage
Preclinical
Lead developer
China Pharmaceutical University
01

Overview

China Pharma Univ. Wee1 compound 12h: sourced facts only. name: "Here, we report the discovery of 12h, a highly selective and potent Wee1 inhibitor with a favorable pharmacokinetic profile." [PMID:38847373]; target: "Here, we report the discovery of 12h, a highly selective and potent Wee1 inhibitor with a favorable pharmacokinetic profile." [PMID:38847373]; developer: "School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, P.R. China." [PMID:38847373]; stage: "12h showed strong antiproliferative effects against Lovo cells, a colorectal cancer cell line, both in vitro and in vivo." [PMID:38847373]

02

Targets

WEE1 (WEE1 G2 checkpoint kinase)

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