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Chinese Academy of Medical Sciences and Peking Union Medical College CXCR2 compound 9b
- Development stage
- Unknown
- Lead developer
- Chinese Academy of Medical Sciences and Peking Union Medical College
01
Overview
Chinese Academy of Medical Sciences and Peking Union Medical College CXCR2 compound 9b: sourced facts only. name: "Structure-activity relationship studies resulted in two lead compounds 9b and 11h, which demonstrated double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch in an in vivo setting." [PMID:34676759]; target: "Structure-activity relationship studies resulted in two lead compounds 9b and 11h, which demonstrated double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch in an in vivo setting." [PMID:34676759]; developer: "State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China." [PMID:34676759]; stage: "More importantly, 9b and 11h dose-dependently inhibited the tumor growth through oral administration in the Pan02 mouse model." [PMID:34676759]
02
Targets
CXCR2 (C-X-C Motif Chemokine Receptor 2)
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