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This investigational Chinese herbal medicine formulation is being developed by the China Academy of Chinese Medical Sciences for the treatment of primary insomnia. The formulation is derived from a research effort at the Prestigious Chinese Clinician Research Laboratory of Guang'anmen Hospital to identify and standardize effective "core drug patterns" from the clinical prescriptions of expert traditional Chinese medicine (TCM) practitioners. Administered as herbal concentrate-granules, the core formulation identified in preliminary retrospective research includes a combination of herbs such as *Ziziphus spinosa* (Fried semen Ziziphi Spinosae), *Poria cocos* (Tuckahoe), *Polygala tenuifolia*, and *Angelica sinensis*. The treatment is designed to be taken twice daily and aims to provide a standardized alternative to individualized TCM prescriptions for insomnia.
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