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Chitogel CSK-4 is a biomaterial-based medical device composed of chitosan succinamide, a modified form of chitosan derived from crustacean chitin. It is designed as a hydrogel middle ear packing material for use during tympanoplasty surgery to repair tympanic membrane perforations. Developed and evaluated by the Henry Ford Health System, the material serves as a support structure, hemostatic agent, and wound-healing promoter. It aims to reduce acute inflammation and long-term fibrosis compared to traditional materials like Gelfoam. The hydrogel works by providing a physical scaffold that prevents scarring and promotes mucosal healing in the middle ear and external canal.
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