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This combination therapy represents the standard conventional therapy protocol utilized at Shahid Beheshti University of Medical Sciences for the management of corneal epithelial defects following diabetic vitrectomy. The regimen consists of three primary components: chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis; betamethasone, a potent corticosteroid used to mitigate ocular inflammation; and homatropine, an antimuscarinic agent that serves as a cycloplegic to prevent synechiae and alleviate pain associated with ciliary spasm. In clinical trial contexts, this combination is typically administered as topical eye drops to promote corneal healing and prevent postoperative complications such as infection and excessive inflammation.
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