Drug intelligence / Profile preview

ChloraPrep AQ

Development stage
Unknown
Lead developer
Becton Dickinson
Modality
Small Molecules
Administration
Topical
01

Overview

ChloraPrep AQ is a brand-specific topical antiseptic formulation consisting of 2% w/v chlorhexidine gluconate (CHG) in an aqueous (water-based) vehicle. Developed by Becton, Dickinson and Company (BD) following the acquisition of CareFusion and C. R. Bard, this formulation is distinguished from the standard ChloraPrep product by the absence of isopropyl alcohol. It is specifically designed for preoperative skin preparation in clinical settings where alcohol-based solutions are contraindicated or undesirable, such as in neonatal care, on sensitive tissues, or near mucous membranes. The antimicrobial action of ChloraPrep AQ is derived from chlorhexidine's ability to bind to and disrupt microbial cell membranes, leading to the leakage of intracellular components and cell death. It provides broad-spectrum bactericidal activity and is noted for its persistence on the skin, maintaining antimicrobial efficacy for up to 48 hours after application.

Brand names
ChloraPrep AQ
Other names
aqueous chlorhexidine gluconate 2%chlorhexidine gluconate 2% aqueous solution
02

Targets

LPS (Lipopolysaccharide)

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