Drug intelligence / Profile preview

chlorhexidine gluconate + nepidermin + silver sulfadiazine

Development stage
Unknown
Lead developer
Bharat Biotech
Modality
Peptides, Small Molecules, Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

SLVRGEN is a topical fixed-dose combination product developed by Bharat Biotech for wound care and burn management. It is formulated as a cream or gel containing three active ingredients: nepidermin (recombinant human epidermal growth factor, rhEGF), silver sulfadiazine, and chlorhexidine gluconate. Nepidermin acts as an agonist of the epidermal growth factor receptor (EGFR), stimulating cell proliferation, migration, and tissue regeneration to accelerate wound healing. Silver sulfadiazine and chlorhexidine gluconate provide broad-spectrum antimicrobial and antiseptic activity, preventing and treating infections at the wound site. This synergistic combination accelerates wound closure while protecting regenerating skin cells from silver toxicity.

Brand names
SLVRGEN
Other names
SlvrgenSlvrgen CreamSlvrgen Gel
02

Targets

EGFR T790M (Epidermal growth factor receptor T790M mutant)DHPS (Dihydropteroate synthase)

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