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chlorhexidine gluconate + ethanol
- Development stage
- Phase 4
- Lead developer
- Troikaa Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Troyhexol is a topical antiseptic solution developed and marketed by Troikaa Pharmaceuticals. It is primarily composed of chlorhexidine gluconate and ethanol, a combination designed for rapid and persistent antimicrobial activity. Chlorhexidine gluconate, a biguanide antiseptic, acts by binding to the negatively charged microbial cell wall and disrupting the cytoplasmic membrane, leading to leakage of cellular contents. Ethanol complements this by rapidly denaturing proteins and dissolving lipid membranes. Troyhexol is widely used in clinical environments for surgical hand scrubs, pre-operative skin preparation, and general hand disinfection to prevent healthcare-associated infections.
- Brand names
- Troyhexol
- Other names
- Chlorhexidine Gluconate and Ethanol Solution
02
Targets
Streptococcus mutans cytoplasmic membrane
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