Drug intelligence / Profile preview

chloroquine + A-CQ

Development stage
Unknown
Lead developer
Bayer
Modality
Small Molecules
Administration
Oral
01

Overview

Chloroquine + A-CQ is a combination drug consisting of chloroquine and a second component referred to as "A-CQ." Chloroquine is a 4-aminoquinoline antimalarial agent that works by increasing the levels of heme in the blood, which is toxic to malaria parasites, thereby killing them and stopping infection. It also has activity against amebiasis outside the intestines and has been used for rheumatoid arthritis and lupus erythematosus. The mechanism of action for "A-CQ" cannot be determined from available sources; it may refer to an analog or derivative of chloroquine, but no definitive information on this specific entity was found in current literature or databases[1][2][4]. Therefore, this combination should be considered as containing at least one well-characterized antimalarial small molecule (chloroquine), with incomplete information about the second component.

02

Targets

Heme

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