Chlorotrianisene

Chlorotrianisene is a synthetic nonsteroidal estrogen that functions as an orally active estrogen receptor modulator. It acts as a prodrug, mimicking the action of natural estrogens by binding to and activating estrogen receptors, leading to various physiological responses. While primarily exhibiting estrogenic effects, it also possesses some antiestrogenic activity, classifying it as a selective estrogen receptor modulator (SERM). Additionally, it has been shown to inhibit cyclooxygenase-1 (COX-1) and platelet aggregation. Historically, Chlorotrianisene was used for hormone replacement therapy, menopausal symptoms, and certain types of breast and prostate cancer, but its use has since been discontinued.

Brand names

TaceEstregurAniseneClorotrisinMerbentylTriagen

Other names

ChloortrianisestrolChlorestroloChlorotrianisenumChlorotrianisineChlorotrianizenChlortrianisenChlortrianisestrolChlortrianisoestrolumChlortrianizenClorotrisinHormoniseneKhlortrianizenClorestroloMetaceRianilChlorotrisinTace-fnTris(p-methoxyphenyl)chloroethyleneClorotrianisenoTrianisestrolChlorotris(p-methoxyphenyl)ethyleneEthylene, chlorotris(p-methoxyphenyl)-