Drug intelligence / Profile preview

chlorphenamine + dextromethorphan + paracetamol

Development stage
Unknown
Lead developer
Grupo Farmasierra
Modality
Small Molecules
Administration
Oral
01

Overview

Remidol is a combination non-prescription drug developed and manufactured by Grupo Farmasierra. It is formulated as granules for oral solution and is indicated for the symptomatic relief of common cold and influenza symptoms, including mild to moderate pain, fever, non-productive cough, nasal congestion, and sneezing. The product contains three active ingredients: paracetamol (acetaminophen), which acts as an analgesic and antipyretic; dextromethorphan hydrobromide, a non-opioid antitussive that suppresses the cough reflex; and chlorphenamine maleate, a first-generation antihistamine that reduces nasal secretions and sneezing.

Brand names
Remidol
Other names
chlorphenamine + dextromethorphan + acetaminophenchlorphenamine + dextromethorphan + paracetamolchlorphenamine maleate + dextromethorphan hydrobromide + paracetamolchlorpheniramine + dextromethorphan + acetaminophenchlorpheniramine + dextromethorphan + paracetamolchlorpheniramine maleate + dextromethorphan hydrobromide + acetaminophen
02

Targets

HRH1 (Histamine H1 Receptor)mAChR (Muscarinic acetylcholine receptors)NMDAR (Glutamate receptor ionotropic, NMDA)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)SIGMAR1 (Sigma non-opioid intracellular receptor 1)SERT (Sodium-dependent serotonin transporter)

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