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chlorpheniramine + hydrocodone
- Development stage
- Approved
- Lead developer
- Tris Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Chlorpheniramine + hydrocodone is a fixed-dose combination medication used to treat cough and upper respiratory symptoms associated with allergies or the common cold. Hydrocodone is an opioid cough suppressant that acts directly on the brain's cough center to reduce the urge to cough. Chlorpheniramine is a first-generation antihistamine that blocks histamine H1 receptor, helping relieve symptoms such as runny nose, sneezing, and itchy or watery eyes. This combination provides both antitussive (cough-suppressing) and antihistaminic effects for symptomatic relief in adults and children over 18 years old[1][2][5][6]. The product carries risks of opioid dependence, misuse, and overdose due to its hydrocodone component[4].
- Brand names
- TussiCapsTussionex PennkineticHyTanNovasusS-T Forte 2TussionexVITUZ
- Other names
- hydrocodone/chlorpheniramine
02
Targets
MOR (Mu opioid receptor)HRH1 (Histamine H1 Receptor)
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