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Chlorzoxazone is a centrally acting skeletal muscle relaxant used to relieve discomfort associated with acute, painful musculoskeletal conditions such as muscle strains and sprains. It is typically prescribed as an adjunct to rest, physical therapy, and analgesics. Chlorzoxazone works primarily at the level of the spinal cord and subcortical areas of the brain by inhibiting multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasm. The result is reduced muscle spasm, pain relief, and increased mobility. It does not replace other treatments like exercise or physical therapy[1][2][3][4][5].
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