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CHO-2

Development stage: Unknown
Lead developer: Allergan
Modality: Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration: Ophthalmic

Overview

CHO-2 is an investigational artificial tear formulation developed by Allergan, Inc. for the treatment of dry eye disease. It is a combination product containing 0.5% carmellose sodium, 0.15% hyaluronic acid, and osmoprotectants (glycerin and erythritol). The formulation is designed to lubricate and hydrate the ocular surface, enhance tear film stability, promote corneal epithelial wound healing, and protect ocular surface cells from hyperosmotic stress and inflammation. Its increased hyaluronic acid content results in a higher viscosity compared to a similar formulation, CHO-1.

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