cholecalciferol + lansoprazole

Cholecalciferol + lansoprazole is a combination of two agents with distinct mechanisms and indications. Cholecalciferol (vitamin D3) is a fat-soluble vitamin used as a dietary supplement to prevent or treat vitamin D deficiency and associated bone disorders such as rickets, osteomalacia, and osteoporosis. It acts by promoting calcium absorption in the gut and maintaining adequate serum calcium and phosphate concentrations for normal bone mineralization[8]. Lansoprazole is a proton pump inhibitor (PPI) that reduces gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells. It is indicated for conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, erosive esophagitis, Zollinger-Ellison syndrome, and in combination regimens for Helicobacter pylori eradication[3][4][6]. The combination may be used when both acid suppression therapy and vitamin D supplementation are required; however, there are no known direct pharmacological interactions between these two agents[1][2].

Other names

vitamin D3 + lansoprazole