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cholecalciferol cream
- Development stage
- Phase 4
- Lead developer
- Abiogen
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
Cholecalciferol cream is a topical formulation of Vitamin D3 currently under development by Abiogen for the treatment of various dermatologic conditions. As a Vitamin D3 analogue, cholecalciferol typically functions by binding to and activating the Vitamin D receptor (VDR) in the skin. This activation modulates the proliferation and differentiation of keratinocytes and exerts anti-inflammatory effects, which are therapeutic in conditions such as psoriasis. The product is currently in the preclinical to clinical development phase, representing a specialized formulation of a well-known vitamin for localized dermatological application.
- Other names
- Vitamin D3 creamVitamin D3 topicalcholecalciferol topical
02
Targets
VDR (Vitamin D receptor)
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