choline + trazodone

TRAZAMINE is a combination product consisting of trazodone hydrochloride, a serotonin antagonist and reuptake inhibitor (SARI), and choline, a precursor to the neurotransmitter acetylcholine. Marketed as a kit by Physician Therapeutics LLC, the product typically contains 50mg trazodone hydrochloride tablets alongside choline supplementation. Trazodone functions as a small molecule antidepressant by selectively inhibiting serotonin uptake and antagonizing 5-HT2 receptors, and it is primarily indicated for major depressive disorder (MDD) and associated anxiety. The addition of choline is intended to support neurotransmitter synthesis, although this specific combination has not been approved by the FDA as safe or effective and is marketed as an unapproved drug product.

Brand names

TRAZAMINE

Other names

trazodone hydrochloride + choline