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choline bitartrate + betaine
- Development stage
- Unknown
- Lead developer
- Balchem
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Choline bitartrate + betaine is a nutritional intervention consisting of two small molecule nutrients that serve as methyl donors in one-carbon metabolism. Developed by Columbia University for use in research settings, this combination is being evaluated for its ability to enhance the methylation of inorganic arsenic, thereby facilitating its excretion from the body. By increasing the availability of S-adenosylmethionine (SAM), these supplements aim to improve arsenic detoxification in populations chronically exposed to contaminated drinking water, potentially reducing the risk of arsenic-induced health outcomes such as skin lesions, cardiovascular disease, and cancer.
- Brand names
- Roex Choline Bitartrate with Betaine HCL
- Other names
- choline bitartrate + betaine-Columbia UniversityCholine and Betaine Supplementation
02
Targets
BHMT (Betaine-homocysteine S-methyltransferase)AS3MT (Arsenite methyltransferase)
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