Drug intelligence / Profile preview

choline salicylate

Development stage
Phase 1
Lead developer
Purdue Pharma
Modality
Small Molecules
Administration
Oral, Topical, Otic
01

Overview

Choline salicylate is the choline salt of salicylic acid and belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It acts as an analgesic, antipyretic, and anti-inflammatory agent. Choline salicylate works by inhibiting cyclooxygenase (COX), thereby reducing prostaglandin synthesis responsible for pain, inflammation, and fever. It is used to treat mild to moderate pain, reduce fever and inflammation or swelling in conditions such as arthritis (including rheumatoid arthritis), gout, rheumatic fever, muscle injuries in both adults and children. The drug is available in oral forms for systemic use and topical gels for localized relief (e.g., mouth lesions or dental procedures). At higher doses it can act as an anticoagulant antagonistic to vitamin K[1][4][5][6][8].

Brand names
ARTHROPANOTINUMOTOTALGINAUDAX
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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