Drug intelligence / Profile preview

CholZero

Development stage
Unknown
Lead developer
Nature's Plus
Modality
Small Molecules
Administration
Oral
01

Overview

CholZero is a dietary supplement formulated to support cardiovascular health by maintaining healthy cholesterol levels. Its primary active profile consists of a complex of plant sterols (phytosterols), including beta-sitosterol, campesterol, and stigmasterol. These compounds are structurally analogous to cholesterol and function by competitively inhibiting the absorption of both dietary and biliary cholesterol within the small intestine. By displacing cholesterol from mixed micelles in the intestinal lumen, plant sterols reduce the amount of cholesterol that enters the bloodstream, subsequently lowering low-density lipoprotein (LDL) cholesterol levels. CholZero is typically used as a non-pharmacological adjunct to a heart-healthy diet for individuals managing hypercholesterolemia.

Brand names
CholZero
Other names
Plant sterolsPhytosterols
02

Targets

NPC1L1 (Niemann-pick C1-Like 1 transporter)

Beyond the preview

Go deeper on CholZero.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on CholZero.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call