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Chondrogen (Mesoblast Ltd)
- Development stage
- Unknown
- Lead developer
- Smith & Nephew
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
Chondrogen is an allogeneic cell therapy consisting of donor-derived human mesenchymal stem cells (hMSCs) formulated in a sodium hyaluronan suspension. Originally developed by Osiris Therapeutics and later by Mesoblast, it is administered via intra-articular injection for the regeneration of the meniscus following injury or surgery (such as partial medial meniscectomy). The therapy acts as a cell and tissue replacement, aiming to restore cartilage and prevent the progression of osteoarthritis by providing a regenerative environment within the knee joint. Clinical evaluation has included Phase I/II studies assessing safety and efficacy in meniscal regeneration.
- Brand names
- Chondrogen
- Other names
- Adult Universal Cellhuman mesenchymal stem cellshMSC
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