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CHOP + famotidine
- Development stage
- Phase 3
- Lead developer
- Merck
- Modality
- Small Molecules
- Administration
- Intravenous, Oral
01
Overview
CHOP is a chemotherapy regimen used primarily for non-Hodgkin lymphoma, consisting of cyclophosphamide (C), doxorubicin (H), vincristine (O), and prednisone or prednisolone (P). Famotidine is an H2-receptor antagonist used to reduce stomach acid production. The combination 'CHOP + famotidine' refers to the use of the standard CHOP chemotherapy regimen with the addition of famotidine, likely as supportive care to prevent or treat gastrointestinal side effects such as heartburn or gastritis during cancer treatment. There is no evidence that this combination has a unique name or specific indication beyond supportive care; it is not a recognized therapeutic entity but rather a pragmatic clinical practice.
- Other names
- CHOP plus famotidineCHOP and famotidine
02
Targets
HRH2 (Histamine H2 Receptor)DNAGR (Glucocorticoid receptor)TUBB (Tubulin (alpha and beta subunits))
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