Drug intelligence / Profile preview

choriogonadotropin alfa + biotin

Development stage
Unknown
Lead developer
Merck KGaA
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Recombinant Proteins and Enzymes, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Subcutaneous (choriogonadotropin Alfa), Intramuscular (choriogonadotropin Alfa, Some Formulations), Oral (biotin), Intravenous (biotin, Rarely)
01

Overview

**Choriogonadotropin alfa + biotin** is a combination product that would contain both choriogonadotropin alfa, a recombinant form of human chorionic gonadotropin hormone used primarily to induce ovulation and treat female infertility, and biotin, a water-soluble B vitamin (vitamin B7) known as a coenzyme for carboxylase enzymes involved in fatty acid synthesis, amino acid metabolism, and gluconeogenesis. Choriogonadotropin alfa works by binding to and activating the luteinizing hormone/chorionic gonadotropin receptor, mimicking the action of endogenous luteinizing hormone to induce ovulation in females. Biotin serves as an essential cofactor for metabolic enzymes and is clinically relevant for treating or preventing biotin deficiency, but is not a standard treatment for infertility or reproductive indications. There is no evidence of a marketed or clinically developed combination of these two agents; this entry describes their known pharmacology as monocomponents[1][2][3][6].

02

Targets

LHCGR (Luteinizing hormone/choriogonadotropin receptor)

Beyond the preview

Go deeper on choriogonadotropin alfa + biotin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on choriogonadotropin alfa + biotin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call