Drug intelligence / Profile preview

choriogonadotropin alfa + epoetin alfa

Development stage
Preclinical
Lead developer
Amgen
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous, Intravenous
01

Overview

**Choriogonadotropin alfa + epoetin alfa** is a combination of two recombinant protein biologics: choriogonadotropin alfa and epoetin alfa.\n- **Choriogonadotropin alfa** is a recombinant form of human chorionic gonadotropin (hCG) used primarily to induce ovulation in female infertility. It acts as a luteinizing hormone receptor agonist to stimulate ovulation, luteinization, and steroid production in the ovaries, mimicking the physiologic actions of endogenous hCG[3].\n- **Epoetin alfa** is a recombinant human erythropoietin analog that stimulates erythropoiesis (red blood cell production) by acting on the erythropoietin receptor in bone marrow, primarily used to treat anemia associated with chronic kidney disease, myelosuppressive chemotherapy, and certain other conditions[2][4].\nThere is no evidence of a marketed or clinically tested combination product of these two biologics as a fixed co-formulation. Therefore, this refers to concomitant use of these two agents, most likely in a research, fertility, or supportive care setting, but not as a single, branded pharmaceutical entity.

Other names
hCG + epoetin alfachorionic gonadotropin + epoetin alfachoriogonadotropin alfa + epoetin alfa
02

Targets

FSHR (Follicle-stimulating hormone receptor)TSHR (Thyroid-stimulating hormone receptor)

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