Drug intelligence / Profile preview

Chrono-Indocid

Development stage
Unknown
Lead developer
HAC Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Chrono-Indocid is a chronotherapeutic, extended-release formulation of indomethacin, a nonsteroidal anti-inflammatory drug (NSAID). Developed and marketed by H.A.C. Pharma, it is designed to provide sustained release of the active ingredient, which is particularly beneficial for managing nocturnal and early morning symptoms of inflammatory conditions. The drug works by inhibiting the cyclooxygenase enzymes COX-1 and COX-2, leading to a reduction in prostaglandin synthesis. It is approved for the treatment of various rheumatological and inflammatory conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, and low-back pain, as well as for post-operative pain and primary dysmenorrhea.

Brand names
Chrono-Indocid
Other names
indomethacinindometacine
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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