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chrysanthemum extract + eucommia bark extract
- Development stage
- Unknown
- Lead developer
- Beijing Tong Ren Tang
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Chrysanthemum extract + eucommia bark extract is a botanical combination frequently utilized in traditional Chinese medicine (TCM) and as a dietary supplement for the management of hypertension and cardiovascular health. The extract from *Chrysanthemum morifolium* (Ju Hua) is rich in flavonoids such as luteolin and apigenin, which provide antioxidant and anti-inflammatory effects. The bark of *Eucommia ulmoides* (Du Zhong) contains bioactive compounds like geniposidic acid and pinoresinol diglucoside, which have been shown to inhibit ACE activity and enhance nitric oxide-mediated vasodilation. Together, these extracts work synergistically to support healthy blood pressure levels, improve lipid metabolism, and provide neuroprotective benefits. While widely used in East Asia, the combination is primarily marketed as a nutraceutical rather than a regulated pharmaceutical drug in Western jurisdictions.
- Other names
- Chrysanthemum morifolium extract + Eucommia ulmoides bark extractJu Hua + Du Zhong
02
Targets
ACE (Angiotensin Converting Enzyme)NO2- (Nitrite)
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