Drug intelligence / Profile preview

chrysanthemum flower oil

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Inhalation, Oral
01

Overview

Chrysanthemum flower oil is an essential oil obtained through steam distillation or solvent extraction from the flowering heads of plants in the *Chrysanthemum* genus, most notably *Chrysanthemum morifolium* and *Chrysanthemum indicum*. In Traditional Chinese Medicine (TCM), it is valued for its cooling properties and is frequently used to treat symptoms associated with 'wind-heat,' such as headaches, dizziness, and ocular inflammation. The oil is a complex mixture of bioactive volatile compounds, including monoterpenes like camphor, borneol, and 1,8-cineole, as well as various sesquiterpenes and flavonoids. Pharmacologically, it demonstrates significant anti-inflammatory, antioxidant, and antimicrobial activities. Its mechanism of action involves the inhibition of pro-inflammatory mediators, including tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), primarily through the suppression of the NF-κB signaling pathway. It is also utilized in aromatherapy for its purported sedative and anxiolytic effects.

Brand names
Ju Hua Oil
Other names
Chrysanthemi Flos oilChrysanthemum indicum oilChrysanthemum morifolium oilWild chrysanthemum oilEssential oil of chrysanthemum
02

Targets

IL-6 (Interleukin 6)NF-κBTNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NOS2 (Nitric Oxide Synthase 2)

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