chrysanthemum morifolium extract

Chrysanthemum morifolium extract is a botanical extract from the flower of Chrysanthemum morifolium, widely used in traditional Chinese medicine and as an herbal supplement. It contains diverse bioactive compounds, notably flavonoids (such as linarin, apigenin, luteolin), terpenoids, and phenylpropanoids. The extract exhibits multiple pharmacological actions, including antimicrobial, anti-inflammatory, antioxidant, immunomodulatory, neuroprotective, anti-diabetic/anti-obesity, anti-lipidemic, and anti-osteoporotic effects[1][2][3][4]. Mechanistically, it modulates inflammatory pathways (e.g., downregulating NF-κB and pro-inflammatory cytokines including IL-6 and TNF-α, and upregulating anti-inflammatory cytokines such as IL-10 and TGF-β1), enhances antioxidant defenses (e.g., increasing SOD, CAT, GSH, activating Nrf2/HO-1 signaling), and can act on metabolic transcription factors (e.g., PPAR-α, PPAR-γ, SREBP-1c) to regulate lipid, glucose, and energy metabolism[1][2][4]. Neuroprotective and sedative properties have also been described, including increased sleep duration in animal models[3]. It is primarily developed and manufactured by companies producing traditional herbal supplements, particularly in China and other Asian countries. The extract is marketed as a dietary supplement, herbal tea, and as an ingredient in multi-herbal preparations, but it is not classified as a pharmaceutical drug in most regulatory jurisdictions[5][6].

Other names

Chrysanthemum morifolium flower extractchrysanthemum flower extractJu Hua extractC. morifolium extract