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Chuan Huang Fang
- Development stage
- Phase 2
- Lead developer
- Shanghai Municipal Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Chuan Huang Fang is a Traditional Chinese Medicine (TCM) herbal formula developed primarily by the Shanghai Municipal Hospital of Traditional Chinese Medicine for the treatment and prevention of various renal conditions. It is frequently studied for its nephroprotective effects, particularly in mitigating cisplatin-induced renal impairment and managing chronic kidney disease (CKD), acute-on-chronic kidney injury, and IgA nephropathy. The formula is often used as an adjuvant therapy alongside standard treatments like valsartan or glutathione to improve renal function and reduce inflammation. Clinical trials have explored its efficacy in preventing chemotherapy-induced nephrotoxicity in patients with lung, gastric, and colorectal cancers.
- Brand names
- Chuanhuang Formula 1
- Other names
- Chuanhuang川黄方
02
Targets
CASP3 (Caspase-3)MAPK14 (p38 mitogen-activated protein kinase alpha)
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