Chuangling Ye

Chuangling Ye (CLY) is a traditional Chinese herbal medicine formula primarily utilized for the treatment of chronic inflammatory wounds and ulcers, most notably diabetic foot ulcers (DFU) and plasma cell mastitis abscesses. As a multi-component herbal preparation, it contains approximately 61 active compounds that interact with a broad network of molecular targets. Network pharmacology studies have identified key biological targets including EGFR, TP53, CCND1, IL-1B, and PTGS2, suggesting a mechanism of action that involves modulating inflammatory responses and promoting tissue repair. The formula is typically administered topically as a solution for rinsing or via saturated gauze drainage to improve local inflammatory conditions in abscesses, sinuses, or fistulas.

Other names

Chuang-Ling-Ye疮灵液