Drug intelligence / Profile preview

Chuanhong Zhongfeng Capsule

Development stage
Phase 1
Lead developer
Changchun University of Chinese Medicine
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Chuanhong Zhongfeng Capsule is a Traditional Chinese Medicine (TCM) compound developed by Ren Jixue, a master of national medicine, for the treatment of acute cerebral infarction. The formulation is designed to promote the recovery of neurological function, reduce disability rates, and improve long-term prognosis in patients following a stroke. Clinical research, including Phase 1 trials, has employed 4D Label-free proteomics and PRM technology to investigate the protein-level mechanisms and identify potential biomarkers associated with its therapeutic effects. It is typically administered as an adjunct to basic clinical treatment for stroke.

Brand names
Chuanhong Zhongfeng Capsule
Other names
Chuanhong Zhongfeng
02

Targets

HLA-A (HLA class I histocompatibility antigen A alpha chain)VNN1 (Vanin-1)MBL (Class B metallo-beta-lactamase)Complement (Complement system)

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