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chuanzhitongluojiaonang (The 2nd Affiliated Hospital of Chongqing Medical University)
- Development stage
- Unknown
- Lead developer
- The 2nd Affiliated Hospital of Chongqing Medical University
- Administration
- Oral
01
Overview
Chuanzhitongluojiaonang is a Traditional Chinese Medicine (TCM) hospital preparation developed by The Second Affiliated Hospital of Chongqing Medical University. It is primarily investigated for the treatment of acute ischemic stroke (AIS). The formulation typically contains extracts from *Chuanxiong* (Ligusticum wallichii) and *Shuizhi* (Leech/Hirudo). These components are traditionally used to promote blood circulation and resolve blood stasis. Pharmacologically, ingredients like hirudin from leeches act as potent thrombin inhibitors, while tetramethylpyrazine from Chuanxiong provides vasodilatory and anti-platelet effects. The drug is currently being evaluated in multicenter clinical trials to assess its efficacy and safety in improving neurological outcomes in stroke patients.
- Brand names
- Chuanzhitongluojiaonang
- Other names
- 川蛭通络胶囊Chuanzhi Tongluo Capsule
02
Targets
F2 (Thrombin)
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